Cohort 2 student Neshika Wijewardhane publishes with ‘Proceedings of MARSS – International Conference on Manipulation, Automation and Robotics at Small Scales’ a paper entitled ‘Long-term imaging and spatio-temporal control of living cells using light.’
Neshika had the following to say about the publication:
‘The ability to optically interact with cells on both an individual and collective level has applications from wound healing to cancer treatment. Building systems which can facilitate both localised light illumination and visualisation of cells can however, be challenging and costly. This work takes the DOME, an existing platform for the closed-loop optical control of microscale agents, and adapts the design to support live-cell imaging. Through modifications made to the imaging and projection systems within the DOME, a significantly higher imaging resolution is achieved as well as the ability to customise the light projection wavelengths. Changes to the fundamental design allow for long-term use in an environment of higher temperature and humidity, facilitating the long-term imaging of live cells.
The Dynamic Optical MicroEnviroment (DOME) robotic device is now able to visualise living cells to aid the control of cells using light. This allows us to implement different light patterns and regimes in a closed-loop manner to initiate different cellular dynamics such as cell migration and thus opens the possibilities for treatments in the fields of wound healing specifically but also in cancer and anti-microbial therapy.’
Link to Journal: https://ieeexplore.ieee.org/xpl/conhome/9870245/proceeding